LYSOSOMAL ACID LIPASE DEFICIENCY: A RARE INHERITED DYSLIPIDEMIA BUT POTENTIAL UBIQUITOUS FACTOR IN THE DEVELOPMENT OF ATHEROSCLEROSIS AND FATTY LIVER DISEASE

Lysosomal acid lipase (LAL), encoded by the gene LIPA, is the sole neutral lipid hydrolase in lysosomes, responsible for cleavage of cholesteryl esters and triglycerides into their component parts.Inherited forms of complete (Wolman Disease, WD) or partial LAL deficiency (cholesteryl ester storage disease, CESD) are fortunately rare.Recently, LAL h

Abstract Behaving in accordance with natural cycles is essential for survival.Birds in the temperate regions use the changes of day length to time their behavior.However, at equatorial latitudes the photoperiod remains almost constant throughout the year, and it is unclear which cues songbirds use to regulate behaviors, such Audio Interfaces as sin

The study of non-wetting liquid transport in a nanoporous medium is stimulated by the possible use of this Ginger Tea process to absorb or accumulate mechanical energy.The filling of nanopores of suspended particles with a non-wetting liquid under decay of the unstable state, when the pressure increase rate is much higher than the rate of volume ch